Welcome !

 

Thanks to more than seventy student associations active on EPFL campus, our community enjoys a dynamic place of studies, where diversity invites itself through various events.

Aware of the workload resulting from managing a student association, Educational Affairs provides our students with the tools and resources they need to thrive associative life and make it become compatible with their studies.

La Blockchain arrive sur le campus de l'EPFL!

Blockchain, Bitcoin, Ethereum … ces mots vous sont-ils familiers ? Ces dernières années, les cryptomonnaies ont révélé au yeux de tous les nouvelles opportunités mises en avant par la Blockchain et les systèmes décentralisés.<

WHAT’S ON IN EPFL?

Export event

11:00

18:00

ArtLab B

Thinking Machines. Ramon Llull and the ars combinatoria

The outstanding Catalan philosopher and theologian Ramon Llull (c.1232–1316) encourages us to reread the late Middle Ages. Llull, not only theoretically and linguistically invented a new method of knowledge acquisition, like an engineer, he also mechanized it, and translated it into a machine.

The EPFL instance is curated by: 

  • Prof. Dr. Amador Vega, (Universitat Pompeu Fabra, Barcelona)
  • Prof. Dr., CEO and Director Peter Weibel (ZKM | Karlsruhe)
  • Prof. Dr. Siegfried Zielinski (Berlin University of the Arts)


Llull’s ars combinatoria was a method based on divine intuition for generating truths by means of a logical algebraic language.The method Llull invented was universal in its aspiration and, introduced a modern way of learning. It postulated the unity of the various disciplines of knowledge of his day, and through deduction, argumentation, and dialogue. The reverberations of Lullian thought on technology, art and culture find their present-day corollary in a pedagogical revolution which has “computational thinking” at its core.

In “Thinking Machines” the realms of poetry, literature and art meet those of humanities and scientific research. The drivers that brings this polymath, thinker, philosopher to the EPFL, demonstrate the extent to which Ramon Llull's investigations and prolific production are of profound relevance for our contemporaneity.

Re-curated with the ZKM (Center for Art and Media Karlsruhe).
This exhibition was originally conceived at the CCCB (Centre de Cultura Contemporània de Barcelona).

Entrance free

By: Prof. Dr. Amador Vega, Prof. Dr., CEO and Director Peter Weibel, Prof. Dr. Siegfried Zielinski

Orchestre de la Suisse Romande OSR

Concerts de l'OSR à Beaulieu - billets gratuits réservés aux -25 ans

Grâce à une Fondation privée, l’OSR offre 300 Cartes Jeunes donnant accès gratuitement à 4 places à choix sur ses concerts à Lausanne. Après inscription, les étudiants reçoivent un code qui leur permet de réserver directement leurs 4 billets sur le site de l’OSR. Ils peuvent ensuite se rendre au(x) concert(s) seul ou avec des amis, pour autant que ces derniers aient également moins de 25 ans. Les billets sont imprimés directement à la maison.

Les concerts à choix ont lieu au théâtre Beaulieu Lausanne à 20h15 les jeudis suivants:
– 1er novembre 2018: Gioacchino Rossini, Wolfgang Amadeus Mozart, Piotr Ilyitch Tchäikovski
– 29 novembre 2018: Arthur Honegger, James Macmillan, George Gershwin, Leonard Bernstein
– 10 janvier 2019: Franz Liszt, Alexander Zemlinsky
– 21 février 2019: Béla Bartók, Bedrich Smetana
– 21 mars 2019: Wolfgang Amadeus Mozart, Béla Bartók
– 2 mai 2019: Ludwig Van Beethoven, Dimitri Chostakovitch
– 16 mai 2019: Robert Schumann
>> Programme complet...


Inscription ici (réservé aux étudiants de -25 ans)

By: Orchestre de la Suisse Romande (OSR)

Export event

12:15

13:15

SV 1717

Innate DNA sensing through the cGAS-STING system - Blurring the boundary between PAMP and DAMP

Abstract :
The life of any organism depends on the ability of cells to accurately recognize and eliminate harmful microbes. In order to detect the immense repertoire of pathogenic entities, the innate immune system of mammals has evolved a range of distinct sensing strategies. One major mechanism is based on the recognition of microbial DNA - an invariant and highly immunogenic pathogen-associated molecular pattern (PAMP). Host cells, however, contain abundant sources of self-DNA. In the context of cellular damage or metabolic derangement, “out-of-the-context” self-DNA can elicit potentially damaging inflammatory responses, thus serving as a potent danger-associated molecular pattern (DAMP).
In my laboratory at EPFL, we study primarily the so-called cGAS-STING system - an evolutionary highly conserved innate DNA sensing system. On DNA binding, cGAS is activated to produce a second messenger cyclic dinucleotide (cyclic GMP-AMP), which stimulates the adaptor protein STING to induce innate immune responses. While this process was originally discovered as a crucial component of immune defense against pathogens, recent work has elucidated a pathogenic role for innate DNA sensing in a variety of sterile inflammatory diseases. In this seminar I will give an overview of our contributions to the understanding of the molecular mechanisms underlying innate DNA recognition and highlight how such knowledge may be leveraged to develop innovative new medicines.

Selected References:
Haag et al., Nature 2018 Jul;559(7713):269-273.
Gulen et al., Nature Communications 2017 Sep 5;8(1):427.
Glück et al., Nature Cell Biology 2017 Sep;19(9):1061-1070.
Wassermann et al., Cell Host & Microbe 2015 Jun 10;17(6):799-810.
Ablasser* et al., Nature 2013 Jun 20;498(7454):380-4.

By: Dr Andrea Ablasser